Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of virulence of Botrytis cinerea mutants defective in phytotoxin production is restored by modifying inoculation medium.

mBio - 11 Feb 2026

Qin Si, Shi-Kunne Xiaoqian, Chen Jie, Pieterse Frank P J, Beenen Henriek G, You Yaohua, van Kan Jan A L

Abstract excerpt

Botrydial, botcinic acid, and their derivatives are major phytotoxic metabolites produced by the necrotrophic fungal pathogen Botrytis cinerea. These phytotoxins are able to induce programmed cell death in the host and thereby promote plant susceptibility to B. cinerea. We observed that a ∆bot2∆boa6 double-mutant strain, which synthesizes neither botrydial nor botcinic acid, was almost avirulent on tomato leaves...

Topics

Botrytis
Plant Diseases
Virulence
Solanum lycopersicum
Culture Media
Mycotoxins
Fungal Proteins
Plant Leaves
Mutation
Aldehydes
Bridged Bicyclo Compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 41459966
DOI: 10.1128/mbio.03119-25
PMCID: PMC12892934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of virulence of Botrytis cinerea mutants defective in phytotoxin production is restored by modifying inoculation medium.PMID 41459966Read ↗

Loss of virulence of <i>Botrytis cinerea</i> mutants defective in phytotoxin production is restored by modifying inoculation mediumSemantic proximity Read ↗

Loss of a major toxin gene cluster defines a metabolic schism and host-specific virulence in <i>Botrytis pseudocinerea</i>Semantic proximity Read ↗

Transcriptome analysis and functional validation reveal a novel gene, BcCGF1 , that enhances fungal virulence by promoting infection‐related development and host penetrationSemantic proximity Read ↗

Mutations in γ-aminobutyric acid (GABA) transaminase genes in plants or Pseudomonas syringae reduce bacterial virulence.Semantic proximity Read ↗

Botrytis cinerea mutants deficient in D-galacturonic acid catabolism have a perturbed virulence on Nicotiana benthamiana and Arabidopsis, but not on tomato.Semantic proximity Read ↗

Revealing Hidden Genes in Botrytis cinerea: New Insights into Genes Involved in the Biosynthesis of Secondary MetabolitesSemantic proximity Read ↗

Deciphering the Dynamics of Signaling Cascades and Virulence Factors of B. cinerea during Tomato Cell Wall DegradationSemantic proximity Read ↗

BcIEB1, a Botrytis cinerea secreted protein, elicits a defense response in plants.Semantic proximity Read ↗

<i>Botrytis cinerea</i> infection accelerates ripening and cell wall disassembly to promote disease in tomato fruitSemantic proximity Read ↗

A secreted Botrytis cinerea stage-specific effector promotes virulence by targeting the plant ROS-generating machinerySemantic proximity Read ↗

Characterization of a new, nonpathogenic mutant of Botrytis cinerea with impaired plant colonization capacity.Semantic proximity Read ↗

Secreted glycoside hydrolase BcGH61 from Botrytis cinerea induces cell death by the apoplastic location and triggers intracellular immune perceptionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.