Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Directed evolution of a staphylophage under biofilm and planktonic conditions.

NPJ biofilms and microbiomes - 25 Dec 2025

Valdivia Carlos, Domingo-Calap Pilar

Abstract excerpt

The rise of multidrug-resistant bacteria, particularly biofilm-forming pathogens such as Staphylococcus epidermidis, highlights the urgent need for alternative antimicrobial strategies. Phage therapy, which uses phages to selectively infect and lyse bacterial cells, offers a promising solution. In this study, we evolved the lytic phage vB_Sep_Steph1 under both biofilm and planktonic conditions, using varying...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages
Share to Biofilms
Share to Directed Molecular Evolution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Mutation

Share to Plankton

Share to Staphylococcus epidermidis

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 41444235
DOI: 10.1038/s41522-025-00893-6
PMCID: PMC12847845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Directed evolution of a staphylophage under biofilm and planktonic conditions.PMID 41444235Read ↗

Targeting MDR Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offsSemantic proximity Read ↗

Analysis of Different Parameters Affecting Diffusion, Propagation and Survival of Staphylophages in Bacterial BiofilmsSemantic proximity Read ↗

A new bacteriophage infecting Staphylococcus epidermidis with potential for removing biofilms by combination with chimeric lysin CHAPSH3b and vancomycinSemantic proximity Read ↗

Phage Activity against Planktonic and Biofilm Staphylococcus aureus Periprosthetic Joint Infection IsolatesSemantic proximity Read ↗

Isolation and characterization of methicillin-resistant Staphylococcus aureus phage SPB against MRSA planktonic cells and biofilmSemantic proximity Read ↗

Combined Use of Bacteriophage K and a Novel Bacteriophage To Reduce Staphylococcus aureus Biofilm FormationSemantic proximity Read ↗

Coagulase-Negative Staphylococci phages panorama: Genomic diversity and in vitro studies for a therapeutic use.Semantic proximity Read ↗

Phage Therapy against Staphylococcus aureus: Selection and Optimization of Production Protocols of Novel Broad-Spectrum Silviavirus PhagesSemantic proximity Read ↗

Optimization of Phage-Antibiotic Combinations against Staphylococcus aureus BiofilmsSemantic proximity Read ↗

Clinical phage microbiology: a narrative summarySemantic proximity Read ↗

Characterization and Genome Analysis of Staphylococcus aureus Podovirus CSA13 and Its Anti-Biofilm CapacitySemantic proximity Read ↗

Proteome Reallocation Reveals Dynamics and Mechanisms of Phage Infection and Defense in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.