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Whole Genome Sequencing Analysis Revealed High Genetic Diversity and Drug-Resistant Characteristics of Mycobacterium bovis From Chinese Farms.

Zoonoses and public health - 1 Mar 2026

Li Xinyue, Dong Yuhui, Xing Ruida, Su Dan, Zhao Bing, Pei Shaojun, Cao Xiaolong, Zhang Ruiqing, Zeng Jiangyong, Wang Dongjing, Fan Weixing, Xia Hui, Wang Shengfen, Ou Xichao, Zhao Yanlin

Abstract excerpt

INTRODUCTION: Bovine tuberculosis (bTB) has a certain incidence on farms in China, but little is known about its prevalence and the pathogenic Mycobacterium species. With the increasing application of whole-genome sequencing (WGS), it is now possible to investigate the genomic diversity, lineage distribution, and drug resistance profiles of M. bovis at high resolution. METHODS: In this study, we sequenced 29...

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PMID: 41340165
DOI: 10.1111/zph.70026

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