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Article

Varicella-Zoster Virus Clades Circulating Among Children With Varicella and Adults With Central Nervous System Infection in Japan.

Journal of medical virology - 1 Dec 2025

Higashimoto Yuki, Hattori Fumihiko, Kawamura Yoshiki, Miura Hiroki, Kurauchi Tamaki, Saito Misaki, Shimizu Nana, Hori Ayano, Yoshikawa Akiko, Ihira Masaru, Sadaoka Tomohiko, Kawada Jun-Ichi, Yoshikawa Tetsushi

Abstract excerpt

Varicella-zoster virus (VZV) causes varicella in children, establishes lifelong latency and reactivates to cause herpes zoster later in life. Implementation of routine varicella vaccination in Japan since 2014 has reduced varicella cases, however, breakthrough varicella still occurs. This study aimed to clarify the current distribution of VZV clade among pediatric varicella patients and adults with VZV-associated...

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PMID: 41332334
DOI: 10.1002/jmv.70750

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