Article
Capmatinib for the treatment of METex14 skipping non-small cell lung cancer: retrospective analysis of real-world data from patients receiving compassionate use treatment in Italy.
Clinical and experimental medicine - 18 Nov 2025
Cecere Fabiana Letizia, D'Argento Ettore, Gelsomino Francesco, Pesola Francesco, Bironzo Paolo, Grisanti Salvatore, Bonanno Laura, Spitaleri Gianluca, Valsecchi Diletta, Marcon Ilaria, Cortinovis Diego
Abstract excerpt
In patients with advanced non-small cell lung cancer (NSCLC), MET exon 14 (METex14) skipping mutations are rare and are associated with a poor prognosis. Capmatinib, a selective oral MET inhibitor, was recently approved for the treatment of advanced METex14 skipping NSCLC. However, data from real-world experiences are limited. This was a retrospective analysis using real-world data from Italian patients with...
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