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Article

Clinical trajectories and medication response in TBC1D24-related epilepsies.

Epilepsia - 1 Mar 2026

Mondragon Ealing, Magielski Jan H, Bane Bintou, Nolan JoeyLynn, Ruggiero Sarah M, Armstrong Dallas, Arnold Susan, Sirsi Deepa, Helbig Ingo, McKee Jillian L

Abstract excerpt

OBJECTIVE: Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24-related disorders. METHODS: We performed an analysis of the electronic medical record data of 15...

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Source

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Identifiers

PMID: 41215607
DOI: 10.1111/epi.70013
PMCID: PMC13007820

Genes

TBC1D24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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