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Article

Mitochondrial proteins contribute to the pathogenesis of myasthenia gravis.

Scientific reports - 5 Nov 2025

Cao Fangzheng, Zhang Houwen, Xu Bin, Wang Juan, Wu Bin, Zhou Yu, Yu Jialin, Li Chunrong

Abstract excerpt

Myasthenia gravis (MG) is an autoimmune disorder mediated by B-cells, characterized by muscle weakness and fatigue. Mitochondria, essential for energy production and muscle function, have been implicated in MG. Despite their importance, the exact relationship between mitochondrial proteins (MPs) and MG remains unclear. This study utilized two-sample Mendelian Randomization (TSMR) to investigate potential causal...

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Identifiers

PMID: 41193658
DOI: 10.1038/s41598-025-22607-w
PMCID: PMC12589580

Genes

SCO1
NFU1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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