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Article

Biomedical literature-based clinical phenotype definition discovery using large language models.

Database : the journal of biological databases and curation - 18 Jan 2025

Binkheder Samar, Liu Xiaofu, Wu Michael, Wang Lei, Shendre Aditi, Quinney Sara K, Wei Wei-Qi, Li Lang

Abstract excerpt

Electronic health record (EHR) phenotyping is a high-demand task because most phenotypes are not usually readily defined. The objective of this study is to develop an effective text-mining approach that automatically extracts clinical phenotype definitions-related sentences from biomedical literature. Abstract-level and full-text sentence-level classifiers were developed for clinical phenotype discovery from...

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Identifiers

PMID: 40996710
DOI: 10.1093/database/baaf047
PMCID: PMC12462612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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