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Article

Importance of aggR sequence variants detection for accurate molecular diagnosis of enteroaggregative Escherichia coli.

Microbiology spectrum - 4 Nov 2025

Del Carpio Alejandra M G, Freire Claudia A, Gomes Tânia A T, Abe Cecilia M, Elias Waldir P

Abstract excerpt

Enteroaggregative Escherichia coli (EAEC) is one of the main diarrhea causative agents. This E. coli pathotype is defined by an aggregative adherence pattern observed in HEp-2 cells. Molecular diagnosis is still a challenge due to EAEC genetic heterogeneity. Different publications described primers for aggR and aatA detection to characterize EAEC. Recently, afpR has been suggested as EAEC molecular marker of some...

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Topics

Escherichia coli
Escherichia coli Proteins
Humans
Escherichia coli Infections
DNA Primers
Trans-Activators

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Multiplex Polymerase Chain Reaction

Genetic Variation

Molecular Diagnostic Techniques

Diarrhea

Source

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Identifiers

PMID: 40990484
DOI: 10.1128/spectrum.01441-25
PMCID: PMC12584630

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