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Ocular bacterial microbiome analysis by next-generation sequencing in patients with Stevens-Johnson syndrome and Sjögren's disease: associations with dry eye indices

2 Sept 2025

Abstract excerpt

The ocular surface microbiome plays a crucial role in maintaining immune homeostasis, and its disruption may contribute to mucosal inflammation and autoimmunity. This pilot exploratory study investigated and compared the ocular surface bacterial microbiome in patients with Stevens-Johnson syndrome (SJS), Sjögren's disease (SjD), and healthy controls using next-generation sequencing (NGS) and correlated these...

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PMID: 40907861
DOI: 10.1016/j.exer.2025.110622

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