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Evaluation of targeted next-generation sequencing for microbiological diagnosis of acute lower respiratory infection

18 Aug 2025

Abstract excerpt

Purpose To evaluate the performance of targeted next-generation sequencing (tNGS) in pathogen detection in acute lower respiratory infection. Methods The retrospective study was conducted between July 2023 and May 2024 at the Yantai Yuhuangding Hospital. Patients with acute lower respiratory infections were included. Qualified sputum or bronchoalveolar lavage fluid samples were collected for tNGS and conventional...

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PMID: 40901079
DOI: 10.3389/fmicb.2025.1615965

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