Article
Phenotypic Selectivity of Artificial Intelligence-Enhanced Electrocardiography in Cardiovascular Diagnosis and Risk Prediction.
Circulation - 4 Nov 2025
Croon Philip M, Dhingra Lovedeep S, Biswas Dhruva, Oikonomou Evangelos K, Khera Rohan
Abstract excerpt
BACKGROUND: Artificial intelligence (AI)-enhanced ECG (AI-ECG) models are often designed to detect specific anatomical and functional cardiac abnormalities. Understanding the selectivity of their phenotypic associations is essential to inform their clinical use. Here, we sought to assess whether AI-ECG models function as condition-specific classifiers or broader cardiovascular risk markers. METHODS: We included 4...
Read the complete abstract on PubMedTopics
- Humans
- Female
- Male
- Electrocardiography
- Artificial Intelligence
- Middle Aged
- Phenotype