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Single-cell transcriptomic reconstruction of the human hair cycle: Capturing the temporal dynamics of skin tissue remodeling

29 Aug 2025

Abstract excerpt

The hair cycle is a valuable model for studying tissue remodeling processes in adult mammals. Time course single-cell transcriptomics offers a powerful approach for characterizing changes in cellular states and interactions; however, its application in human tissues remains challenging. Here, we performed single-cell RNA sequencing on 19 human skin tissues, each containing a single hair follicle. We reconstructed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40884793
DOI: 10.1016/j.celrep.2025.116196

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