MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis

Abstract excerpt

BACKGROUND: Endometrial injury (EI) is frequently associated with intrauterine adhesions, endometrial thinning, amenorrhea, and infertility. In recent years, stem cells and their exosomes have been shown to have significant tissue repair efficacy. However, the role and probable mechanism of human umbilical cord mesenchymal stem cells (hUMSC-Exo) in endometrial healing remains unclear. METHODS: To build an EI...

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