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Epstein-Barr virus-coded miR-BART19-3p promotes proliferation of EBV-associated gastric cancer by inhibiting GADD45B

25 Aug 2025

Abstract excerpt

BACKGROUND: EBV-associated gastric cancer (EBVaGC) is a distinct molecular subtype of gastric cancer with EBV latency infection. EBV microRNAs, especially rightward transcript (BART) microRNAs, play key roles in the tumor growth of EBVaGC. However, the effects of EBV-miR-BART19-3p in EBVaGC remain largely unknown. METHODS: EBV-miR-BART19-3p was detected by qRT-PCR in EBER in situ hybridization positive gastric...

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PMID: 40855561
DOI: 10.1186/s12967-025-06955-9

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