Genomic epidemiology of enteropathogenic Escherichia coli in southwestern Nigeria.

doi:10.1371/journal.pntd.0013442

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Article

Genomic epidemiology of enteropathogenic Escherichia coli in southwestern Nigeria.

PLoS neglected tropical diseases - 1 Aug 2025

Akinlabi Olabisi C, Dada Rotimi A, Olayinka Ademola A, Oginni-Falajiki Ibukunoluwa O, Bejide Oyeniyi S, Adewole Pelumi D, Thomson Nicholas R, Aboderin Aaron O, Okeke Iruka N

Abstract excerpt

BACKGROUND: Enteropathogenic Escherichia coli (EPEC) are etiological agents of diarrhea. We studied the genetic diversity and virulence factors of EPEC in southwestern Nigeria, where this pathotype is rarely characterized. METHODOLOGY/PRINCIPAL FINDINGS: EPEC isolates (n = 96) recovered from recent southwestern Nigeria diarrhea case-control studies were whole genome-sequenced using Illumina technology. Genomes...

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Topics

Nigeria
Enteropathogenic Escherichia coli
Humans
Escherichia coli Infections
Phylogeny
Diarrhea

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Multilocus Sequence Typing

Virulence Factors

Polymorphism, Single Nucleotide

Genome, Bacterial

Child, Preschool

Infant

Male

Case-Control Studies

Female

Child

Whole Genome Sequencing

Molecular Epidemiology

Source

Open in PubMed Open full text

Identifiers

PMID: 40845059
DOI: 10.1371/journal.pntd.0013442
PMCID: PMC12404642

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