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Diversity and spillover risk of swine acute diarrhea syndrome and related coronaviruses in China and Southeast Asia.

mBio - 10 Sept 2025

Latinne Alice, Zhang Li-Biao, Firth Cadhla, Zhu Guangjian, Olival Kevin J, Sánchez Cecilia A, Chen Shirley, Ross Noam, Li Hongying, Chmura Aleksei A, Daszak Peter

Abstract excerpt

Bats are the reservoir hosts of emerging coronaviruses (CoVs) affecting human and livestock health. We assessed the diversity, evolution, and geographic distribution of two alphacoronaviruses (subgenus Rhinacovirus) with considerable potential for emergence: swine acute diarrhea syndrome coronavirus (SADS-CoV), which has caused large outbreaks in pigs in China and can infect primary human airway epithelial cells...

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PMID: 40827904
DOI: 10.1128/mbio.01197-24
PMCID: PMC12421832

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