Genomic analysis of Mycobacterium abscessus isolates from non-cystic fibrosis patients in Thailand: phylogeny, subspecies distribution, and antimicrobial resistance profiles.

Abstract excerpt

BACKGROUND: Mycobacterium abscessus (MABS) is a clinically significant nontuberculous mycobacterium, and its drug resistance poses substantial therapeutic challenges. Comprehensive genomic and phenotypic analyses are essential for elucidating the mechanisms underlying this resistance and enhancing understanding of its epidemiology. METHODS: Whole-genome sequencing (WGS) using the Illumina platform was conducted...

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