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Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism

4 Aug 2025

Abstract excerpt

BACKGROUND: Sphingolipid metabolism (SM) is linked to acute myocardial infarction (AMI), but its role remains unclear. This study explored SM-related genes (SMRGs) in AMI to support clinical diagnosis. METHODS: We analyzed datasets GSE48060 and GSE123342 to identify differentially expressed genes (DEGs) and key module genes. Protein-protein interaction (PPI) network analysis and machine learning were used to...

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PMID: 40760666
DOI: 10.1186/s41065-025-00515-3

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