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Beyond black and white: dissecting the genetic basis of skin depigmentation in Nellore cattle.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2025

Campos Milena A F, de Oliveira Hinayah Rojas, de Camargo Gregorio M F, Mulim Henrique A, Cardoso Diercles Francisco, Costa Raphael Bermal

Abstract excerpt

Depigmentation defects in cattle are characterized by the absence of pigment in specific skin regions, increasing susceptibility to health issues and often leading to early culling. In Nellore cattle, depigmentation is primarily observed at the tail tip, mucous membranes, and as small patches across the body. This study aimed to estimate genetic parameters and perform a genome-wide association study (GWAS) for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40760343
DOI: 10.1007/s00335-025-10153-9
PMCID: PMC12578768

Genes

MITF
EDNRB
KIT

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