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Evolutionarily divergent nidovirus with an exceptionally large genome identified in Pacific oysters undergoing mass mortality

4 Aug 2025

Abstract excerpt

Metatranscriptomic data from a mass-mortality event of adult Pacific Oysters, Crassostrea ( Magallana ) gigas , the most widely cultivated shellfish globally, revealed a nidovirus shown to replicate in a bivalve, Pacific Oyster Nidovirus 1 (PONV1). At 64,331 bp of linear bisegmented, positive-sense single-stranded RNA, PONV1 has one of the largest genomes reported for an RNA virus. Moreover, transcriptomic data...

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PMID: 40758866
DOI: 10.1073/pnas.2426923122

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