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miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling

18 Jul 2025

Abstract excerpt

Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferation of keratinocytes, immune dysregulation, and abnormal epidermal differentiation. Its pathogenesis involves complex interactions among keratinocytes, fibroblasts, T cells, and myeloid cells, where dynamic cytoskeletal and extracellular matrix changes critically mediate intercellular communication. Emerging evidence highlights the...

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PMID: 40756258
DOI: 10.3389/fcell.2025.1608902

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