The Association Between Thromboembolic Events and ALK, ROS1, RET Rearrangements or EGFR Mutations in Patients With Advanced Lung Adenocarcinoma: A Retrospective Cohort Study.

doi:10.1111/1759-7714.70141

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The Association Between Thromboembolic Events and ALK, ROS1, RET Rearrangements or EGFR Mutations in Patients With Advanced Lung Adenocarcinoma: A Retrospective Cohort Study.

Thoracic cancer - 1 Aug 2025

Qian Xiaohan, Fu Mengjiao, Zheng Jing, Chen Junjun, Cai Cuihong, Zhou Jianya, Zhou Jianying

Abstract excerpt

INTRODUCTION: Previous studies have reported inconsistent findings regarding the associationbetween ALK and ROS1 rearrangements in lung cancer and thromboembolic risk. This retrospective study aimed to investigate this association in advanced lung adenocarcinoma patients with ALK, ROS1, RET rearrangements, and EGFR mutations. MATERIALS AND METHODS: We retrospectively collected information on patients with...

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Topics

Humans
Male
Retrospective Studies
Female
Middle Aged
Proto-Oncogene Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adenocarcinoma of Lung

Lung Neoplasms

ErbB Receptors

Mutation

Thromboembolism

Protein-Tyrosine Kinases

Gene Rearrangement

Anaplastic Lymphoma Kinase

Aged

Proto-Oncogene Proteins c-ret

Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 40751559
DOI: 10.1111/1759-7714.70141
PMCID: PMC12317367

Genes

ROS1
ALK
EGFR
RET
CRP

Provenance

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