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Microplastic exposure induces epithelial barrier alterations and increases collagen deposition in a 3D human endometrial model in vitro

1 Aug 2025

Abstract excerpt

PURPOSE: To investigate the effects of microplastics (MPs) on the human endometrium in vitro. METHODS: A predictive 3D endometrial in vitro model was generated using highly porous scaffolds where human endometrial stromal (hESC) and epithelial (hEEC) cells were co-cultured for 35 days. The newly generated endometrial barrier was then exposed to different MP concentrations (from 0.25 to 50 mg/ml) for 24 h and 48...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40748567
DOI: 10.1007/s10815-025-03566-7

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