Bioinformatic analysis identifies LPL as a critical gene in diabetic kidney disease via lipoprotein metabolism

Abstract excerpt

Background: Diabetic kidney disease (DKD) is a common and serious complication of diabetes, affecting approximately 40% of patients with the condition. The pathogenesis of DKD is complex, involving multiple processes such as metabolism, inflammation, and fibrosis. Given its increasing incidence and associated mortality, there is an urgent need to identify novel pathogenic genes and therapeutic targets. Methods:...

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