Pathway-level convergence: an underexplored aspect of convergent evolution.

Abstract excerpt

The extent to which evolution is repeatable at the genetic level remains a central question in biology. Convergent adaptations can arise through mutations in homologous genes, changes in different genes within the same pathways, or distinct molecular routes. Most research has focused on gene-level convergence, whereas relatively little is known about the prevalence of pathway-level convergence. Here, we...

Topics

• Humans
• Animals
• Evolution, Molecular
• Mutation
• Adaptation, Physiological
• Systems Biology