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Gastric neoplasm with foveolar-cell differentiation in Helicobacter pylori-naïve patients.

1 Mar 2026

Abstract excerpt

-naïve individuals with long-term proton pump inhibitor use. A syndromic form, resembling flat-type FGAs, is also associated with FAP and GAPPS. Histologically, FGPD features dysplasia confined to the superficial foveolar epithelium and mucus neck cells overlying fundic gland polyps, with APC mutations detected in approximately 50% of cases. This review explores the clinicopathological and molecular...

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PMID: 40728066
DOI: 10.14670/hh-18-966

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