Associations Between G8 Geriatric Screening Score, Charlson Comorbidity Index, AI-Based Age Phenotype, and Overall Survival in Older Adults With Stage I-II Non-Small Cell Lung Cancer.

doi:10.1016/j.ijrobp.2025.07.1431

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Article

Associations Between G8 Geriatric Screening Score, Charlson Comorbidity Index, AI-Based Age Phenotype, and Overall Survival in Older Adults With Stage I-II Non-Small Cell Lung Cancer.

International journal of radiation oncology, biology, physics - 1 Dec 2025

Thompson Leah L, Amin Priya M, Shah Sanjana, Lipson Sarah M, Yoon Jenny, Lee Grace, Anabaraonye Nancy, Gregg Austin T, Jiang Sharon, Baxter Emilie, Florissi Caterina, He John, Saraf Anurag, Nipp Ryan D, Bontempi Dennis, Haugg Fridolin, Aerts Hugo J W L, Mak Raymond H

Abstract excerpt

PURPOSE: Comprehensive geriatric assessment can identify older adult oncology patients at high risk for adverse outcomes, but is variably feasible. Therefore, we assessed whether an abridged geriatric vulnerability model incorporating abstracted G8 score (G8), Charlson Comorbidity Index (CCI), and FaceAge (an AI-based aging measure) was associated with all-cause mortality or falls risk in patients undergoing...

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Topics

Humans
Aged
Carcinoma, Non-Small-Cell Lung
Lung Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Female

Aged, 80 and over

Geriatric Assessment

Accidental Falls

Radiosurgery

Comorbidity

Neoplasm Staging

Phenotype

Age Factors

Source

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Identifiers

PMID: 40720998
DOI: 10.1016/j.ijrobp.2025.07.1431
PMCID: PMC12444770

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