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Genomic and Phenotypic Characterization of Mupirocin-resistant Staphylococcus aureus Clinical Isolates

30 Jun 2025

Abstract excerpt

Abstract Background Colonization with Staphylococcus aureus is a risk factor for subsequent infection. Decolonization with the topical antibiotic mupirocin is effective and reduces the risk of subsequent S. aureus infection for both methicillin-sensitive and methicillin-resistant (MRSA) strains but may select for mupirocin-resistant isolates. Methods We characterized oxacillin and mupirocin susceptibility amongst...

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PMID: 40698033
DOI: 10.1093/ofid/ofaf374

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