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Article

Machine Learning-Driven Identification of Blood-Based Biomarkers and Therapeutic Agents for Personalized Ischemic Stroke Management.

Journal of cardiovascular translational research - 1 Aug 2025

Liu Jing, Bai Congxia, Yang Haitao, Song Li, Xu Haochen, Sun Yingying, Suo Miaomiao, Gao Ziyu, Li Hao, Wang Feng, Chen Jingzhou

Abstract excerpt

Ischemic stroke (IS) is the most common subtype of stroke. However, reliable blood biomarkers for early diagnosis remain unavailable. This study developed a predictive model based on peripheral blood (PB) biomarkers. PB samples from two independent cohorts including IS patients and healthy controls (CTR) were analyzed by RNA sequencing (RNA-seq). 69 mRNAs were consistently and significantly dysregulated in IS...

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Identifiers

PMID: 40694178
DOI: 10.1007/s12265-025-10635-w
PMCID: PMC12436529

Genes

BCL2A1
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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