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Article

Dysregulation of metabolites and high-altitude illnesses development under plateau conditions

2 Jul 2025

Abstract excerpt

Background: Under plateau conditions, changes in metabolite levels can affect cellular signal transduction, protein activity, and gene expression, thereby inducing a series of physiopathological changes. Altered metabolite signaling in plateau environments may be associated with the onset and progression of high-altitude illnesses. This review summarizes the effects of a plateau environment on diseases, the...

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PMID: 40671709
DOI: 10.3389/fphys.2025.1600374

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