Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calprotectin as a Biomarker for Infectious Diseases: A Comparative Review with Conventional Inflammatory Markers

4 Jul 2025

Abstract excerpt

Calprotectin, the most abundant cytosolic protein in neutrophils, is a S100A8/S100A9 heterodimer released during immune activation. It inhibits bacterial growth by binding to essential metal ions and contributes to inflammation and leukocyte migration. This review highlights calprotectin's potential as a diagnostic marker for bacterial infections and inflammation. Clinical trials demonstrate that calprotectin is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers in Disease Mechanisms
Share to Neonatal Respiratory Health Research
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40650251
DOI: 10.3390/ijms26136476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calprotectin as a Biomarker for Infectious Diseases: A Comparative Review with Conventional Inflammatory MarkersPMID 40650251Read ↗

Fecal calprotectin: beyond intestinal organic diseases.Semantic proximity Read ↗

Emerging Biomarkers for the Diagnosis and Monitoring of Inflammatory Bowel Diseases.Semantic proximity Read ↗

Synovial fluid S100A8, S100A9, and HNP 1-3 in the diagnosis of periprosthetic joint infection: a prospective, double-blind trialSemantic proximity Read ↗

The endogenous Toll–like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancerSemantic proximity Read ↗

Zebrafish do not have calprotectinSemantic proximity Read ↗

Development and validation of a latex particle-enhanced turbidimetric immunoassay for fecal calprotectin Bioprocessing and BioengineeringSemantic proximity Read ↗

Elevated fecal calprotectin is associated with gut microbial dysbiosis, altered serum markers and clinical outcomes in older individualsSemantic proximity Read ↗

In vitro/vivo Mechanism of Action of S100A12 in Sepsis-induced ARDSSemantic proximity Read ↗

Identification of pyroptosis-related gene S100A12 as a potential diagnostic biomarker for sepsis through bioinformatics analysis and machine learningSemantic proximity Read ↗

Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?Semantic proximity Read ↗

Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infectionsSemantic proximity Read ↗

COVID-19 Pathology Sheds New Light on Balance between Neutrophil Proteases and Their InhibitorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.