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Expression of urinary exosomal miR-136-5p in diabetic kidney disease and evaluation of its clinical diagnostic value

4 Jul 2025

Abstract excerpt

Diabetic kidney disease (DKD) has become a major cause of chronic kidney disease and end-stage renal disease. Numerous studies have indicated that exosomal miRNAs play a crucial role in the pathophysiological processes of DKD. We screened differentially expressed miRNAs in urinary exosomes from patients with DKD using the GEO database and performed PCR validation both in patients who were pathologically diagnosed...

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PMID: 40615520
DOI: 10.1038/s41598-025-06810-3

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