Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subtractive proteomics and molecular docking identify therapeutic targets and drug candidates in drug resistant Klebsiella Michiganensis THO-011

3 Jul 2025

Abstract excerpt

Klebsiella michiganensis, an emerging multidrug-resistant pathogen, poses a significant public health threat. This study employed subtractive genomics to identify potential therapeutic targets in K. michiganensis THO-011. From 4,024 predicted open reading frames, we identified non-redundant, human non-homologous proteins and analyzed them for essentiality, subcellular localization, and metabolic pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Drug Discovery Methods
Share to Microbial Natural Products and Biosynthesis
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40610643
DOI: 10.1038/s41598-025-08107-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subtractive proteomics and molecular docking identify therapeutic targets and drug candidates in drug resistant Klebsiella Michiganensis THO-011PMID 40610643Read ↗

Subtractive genomics and comparative metabolic pathways profiling revealed novel drug targets in Ureaplasma urealyticumSemantic proximity Read ↗

Subtractive Genomics Approach for Identification of Novel Therapeutic Drug Targets in Mycoplasma genitaliumSemantic proximity Read ↗

Multicenter comparative genomic study of Klebsiella oxytoca complex reveals a highly antibiotic-resistant subspecies of Klebsiella michiganensisSemantic proximity Read ↗

Antibiotic resistance in Neisseria gonorrhoeae: broad-spectrum drug target identification using subtractive genomicsSemantic proximity Read ↗

Computational Study for the Identification of Novel Therapeutic Targets in Haemophilus influenzae by Subtractive Genomics ApproachSemantic proximity Read ↗

Novel therapeutic targets identification of Delftia tsuruhatensis strain TR1180 employing subtractive genomics approachSemantic proximity Read ↗

Genome-wide Core Proteome Analysis of Brucella melitensis Strains for Potential Drug Target PredictionSemantic proximity Read ↗

Identification and Characterization of Potential Therapeutic Candidates in Emerging Human Pathogen Mycobacterium abscessus: A Novel Hierarchical In Silico ApproachSemantic proximity Read ↗

<i>In silico</i> Identification of Novel Common Drug Targets Against Four Infectious <i>Acinetobacter</i> SpeciesSemantic proximity Read ↗

Integrated Bioinformatics-Based Subtractive Genomics Approach to Decipher the Therapeutic Drug Target and Its Possible Intervention against BrucellosisSemantic proximity Read ↗

A bio-informatics approach to identify new drug targets in multidrug-resistant bacteriaSemantic proximity Read ↗

Host-Directed Drug Targeting of Factors Hijacked by PathogensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.