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Maternal gut microbiome interventions to improve maternal and perinatal health outcomes: Target product profile expert consensus and pipeline analysis

2 Jul 2025

Abstract excerpt

OBJECTIVE: To develop a novel Target Product Profile (TPP) outlining the minimum and optimal requirements of probiotics targeting the maternal gut microbiome, create a research and development (R&D) pipeline of maternal microbiome interventions, and identify the highest potential probiotic candidates matching TPP criteria. DESIGN: A mixed-methods study including in-depth interviews, an international survey, and...

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PMID: 40601677
DOI: 10.1371/journal.pone.0321543

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