Article
Challenging and redefining Dollo's law of evolution: re-appearance of lost structures.
BMC ecology and evolution - 1 Jul 2025
Jackman William R, Lynch Vincent J, Gibert Yann
Abstract excerpt
According to a modern interpretation of Dollo's Law of irreversibility in evolution, a lost structure, is unable to reappear in evolution due to the accumulation of mutations in the genes required for its formation. However, several reports have challenged this law, even in vertebrates. Lost structures have been reported to re-appear in natural populations, as well as through spontaneous mutations, genetic...
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