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Inflammation-related gene ITGA5 affects the healing of diabetic foot ulcers through PI3K-AKT signaling pathway

22 Jun 2025

Abstract excerpt

BACKGROUND: Diabetic foot ulcers (DFU), a severe complication of diabetes, are characterized by impaired healing due to chronic inflammation and dysregulated cellular processes. Identifying inflammation-related biomarkers and their mechanisms is critical for improving DFU management. METHODS: Bioinformatics analysis of GEO datasets (GSE7014, GSE29221, GSE147890) identified inflammation-related differentially...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Diabetic Foot Ulcer Assessment and Management
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40555342
DOI: 10.1016/j.ejphar.2025.177865

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