Epidemiology of aminoglycosides resistance and phenotypic detection of aac(6')-Ib-cr gene in ESBL-producing Enterobacterales in febrile urinary tract infection in children.

Abstract excerpt

OBJECTIVES: ESBL-producing Enterobacterales (ESBL-E) poses a growing challenge in managing febrile urinary tract infections (FUTIs) in children, leaving amikacin as a good probabilistic once-daily and outpatient treatment option. This epidemiological study investigates aminoglycoside resistance patterns among pediatric ESBL-E isolates, with a particular focus on the aac(6')-Ib-cr gene - a common resistance...

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