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Developing a quantitative estimate of muscle age acceleration by a novel phenotypic clock: cross-sectional study in healthy, middle-aged and older adults.

Aging - 9 Jun 2025

Ventura Lucia, Cano Antonella, Morrone Marco, Martinez Gianluca, Boi Anna, Catte Maria Grazia, Mercante Beniamina, Loi Nicola, Yurchyshyn Oksana, Fiorito Giovanni, Solinas Giuliana, Cruciani Sara, Coradduzza Donatella, Maioli Margherita, Zinellu Angelo, Carru Ciriaco, Deriu Franca, Manca Andrea

Abstract excerpt

Sarcopenia is a progressive disease characterized by reductions in muscle mass strength and physical performance. Among the initiatives launched to increase awareness, the European Working Group on Sarcopenia in Older People (EWGSOP) is considered the most influential. This cross-sectional study was planned to develop, in healthy middle-aged and older adults, a novel predictor of sarcopenia based on the...

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PMID: 40500122
DOI: 10.18632/aging.206269
PMCID: PMC12245203

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