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The Involvement of Oral Pathogenic Bacteria, Fusobacterium nucleatum Subspecies animalis in the Pathogenesis of Human Esophageal Adenocarcinoma

1 Jan 2025

Abstract excerpt

Background and Aims While esophageal microbiota is known to be altered in patients with esophageal adenocarcinoma (EAC), specific bacterial species contributing to the pathogenesis remain unclear. We aimed to identify bacteria associated with the pathogenesis of EAC and to investigate their potential role. Methods Microbiota in EAC tissues was explored by 16S-rRNA sequencing. The impact of intratumoral bacteria...

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PMID: 40486267
DOI: 10.1016/j.gastha.2025.100660

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