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Article

Pulmonary veno-occlusive disease: a paradigm of diagnosis and therapeutic challenges in pulmonary hypertension.

Current opinion in pulmonary medicine - 1 Sept 2025

Aguado Benoit, Grynblat Julien, Budhram Brandon, Ghigna Maria-Rosa, Boucly Athenaïs, Antigny Fabrice, Jaïs Xavier, Sitbon Olivier, Savale Laurent, Humbert Marc, Montani David

Abstract excerpt

PURPOSE OF REVIEW: Pulmonary veno-occlusive disease (PVOD) is a rare and life-threatening form of precapillary pulmonary hypertension. This review aims to outline its genetic and environmental risk factors, highlight key diagnostic challenges, and discuss current treatment options. RECENT FINDINGS: PVOD can occur sporadically or as a hereditary autosomal recessive condition with biallelic eukaryotic translation...

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Share to PAH gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40471666
DOI: 10.1097/MCP.0000000000001184

Genes

PAH
EIF2AK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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