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First genomic analysis of a Clostridium perfringens strain carrying both the cpe and netB genes and the proposal of an amended toxin-based typing scheme

19 May 2025

Abstract excerpt

Clostridium perfringens strains are classified into seven toxinotypes (A–G) based on the profiles of the six typing toxin genes. Among these toxins, NetB is known as an important virulence factor for necrotic enteritis in chickens, and its gene, netB, is present only in type G strains. CPE is the enterotoxin that causes food-borne affections in humans, and its gene, cpe, is carried by type F strains and...

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PMID: 40458709
DOI: 10.3389/fmicb.2025.1580271

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