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Navigating complexities of polymorphic microbiomes in endometrial cancer

22 May 2025

Abstract excerpt

The microbiome is key to understanding endometrial cancer (EC) etiology and prevention strategies, implicated in the regulation of estrogen in estrogen-driven cancers. Utilizing robust methodologies in the QIIME 2 platform, we examined 16S rRNA vaginal and rectal microbiome data from an EC cohort: 192 women with benign gynecologic conditions, endometrial hyperplasia, or endometrial cancer. Distinct microbial...

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PMID: 40404643
DOI: 10.1038/s41522-025-00690-1

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