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The Role of Gut Microbiome on Glioblastoma Oncogenesis and Malignant Evolution

24 Mar 2025

Abstract excerpt

Glioblastoma (GBM) remains the most aggressive primary brain tumor, with poor survival outcomes and treatment limited to maximal safe surgical resection, chemotherapy with temozolomide, and radiotherapy. While immunotherapy and targeted treatments show promise, therapeutic resistance and disease progression remain major challenges. This is partly due to GBM's classification as a "cold tumor" with low mutational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40243570
DOI: 10.3390/ijms26072935

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