Heart Failure With Preserved Ejection Fraction Phenotype Is Associated With Early Symptom Onset in Aortic Stenosis and Residual Symptoms After Transcatheter Aortic Valve Implantation.

doi:10.1161/JAHA.124.038786

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Article

Heart Failure With Preserved Ejection Fraction Phenotype Is Associated With Early Symptom Onset in Aortic Stenosis and Residual Symptoms After Transcatheter Aortic Valve Implantation.

Journal of the American Heart Association - 6 May 2025

Venema Constantijn S, van Bergeijk Kees H, Krikken Jan A, van der Werf Hindrik W, van den Heuvel Ad F M, Douglas Yvonne L, Mordi Ify R, Girerd Nicolas, Lang Chim C, Lam Carolyn S P, Leon Martin B, Lipsic Erik, Rienstra Michiel, Voors Adriaan A, Wykrzykowska Joanna J

Abstract excerpt

BACKGROUND: Aortic stenosis can lead to cardiac adaptations and symptoms similar to heart failure with preserved ejection fraction. We hypothesized that a heart failure with preserved ejection fraction phenotype in aortic stenosis is associated with earlier onset of symptoms and reduced symptomatic response after transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS: This retrospective cohort study...

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PMID: 40240943
DOI: 10.1161/JAHA.124.038786
PMCID: PMC12184250

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