Advancing Gut Microbiome Research: The Shift from Metagenomics to Multi-Omics and Future Perspectives

Abstract excerpt

Advancements in NGS technologies have significantly expanded the scope and efficiency of metagenomics, surpassing traditional culture-based methods (Fig. 2).These innovations enable multi-domain microbial analysis through advanced bioinformatics tools, long-read sequencing, single-cell omics, and enhanced culture-based techniques, facilitating deeper insights into microbial diversity, function, and host...

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