Article
Cutaneous manifestations of WHIM syndrome.
The Journal of dermatology - 1 May 2025
Adhanom Rutha, Kim Caleb, Strong Jennifer, Martinez Sophia, Kong Heidi H, Brownell Isaac, Murphy Philip M, McDermott David H, Castelo-Soccio Leslie
Abstract excerpt
Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) syndrome is a rare immunodeficiency caused by gain-of-function mutations in the chemokine receptor CXCR4. While human papillomavirus (HPV) skin infection (warts) is the dermatological hallmark of the disease, individuals with WHIM have high rates of other skin manifestations that may aid early diagnosis and management. This study was a...
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- Humans
- Male
- Female
- Adult
- Child
- Adolescent
- Middle Aged