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Maternal-offspring brain and tissue cross-talk in preeclampsia: insights from a rat model

7 Apr 2025

Abstract excerpt

This study aimed to investigate the differential metabolic profiles across maternal and offspring brains, serum, and placental tissues in preeclampsia (PE), with a particular focus on elucidating the maternal-offspring brain and tissue cross-talk that may contribute to the complex pathophysiology of PE. PE was induced in rats using the nitric oxide synthase inhibitor N-nitro-L-arginine methyl ester (L-NAME) to...

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PMID: 40192930
DOI: 10.1007/s11011-025-01593-y

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