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Basal ganglia calcification: ‘Fahr’s disease’

1 Apr 2025

Abstract excerpt

Brain calcification is often detected incidentally, but basal ganglia calcification has a wide differential diagnosis, including genetic and acquired causes. Primary familial brain calcification (PFBC) (formerly ‘Fahr’s disease’) refers to neurological disorders characterised by bilateral, symmetrical deposition of calcium-hydroxyapatite crystals in the basal ganglia and other encephalic regions, with a presumed...

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PMID: 40169250
DOI: 10.1136/pn-2024-004258

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