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Article

Distinct Roles of Common Genetic Variants and Their Contributions to Diabetes: MODY and Uncontrolled T2DM.

Biomolecules - 14 Mar 2025

Bazzazzadehgan Shadi, Shariat-Madar Zia, Mahdi Fakhri

Abstract excerpt

Type 2 diabetes mellitus (T2DM) encompasses a range of clinical manifestations, with uncontrolled diabetes leading to progressive or irreversible damage to various organs. Numerous genes associated with monogenic diabetes, exhibiting classical patterns of inheritance (autosomal dominant or recessive), have been identified. Additionally, genes involved in complex diabetes, which interact with environmental factors...

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Share to Diabetes Mellitus, Type 2
Share to Diabetes Treatment and Management

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Associations and Epidemiology

Share to Genetic Predisposition to Disease

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Share to Pancreatic function and diabetes

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Identifiers

PMID: 40149950
DOI: 10.3390/biom15030414
PMCID: PMC11940602

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